
Centre de Neurophysique, Physiologie et Pathologie - CNRS UMR 8119
Université Paris Descartes
45 Rue des Saints Pères
75270 Paris Cedex 06
France
Fax : +33 (0) 1 42 86 20 80
Philippe LIERE
Research Engineer - INSERM
Mass Spectrometry analytical platform, Myelination and Nervous system pathologies
Mass Spectrometry analytical platform, Myelination and Nervous system pathologies
Journal articles
2025
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- Lilith Fischer, Bjarne Paschke, Franziska Gareis, Michael Schumacher, Philippe Liere, et al.. The translocator protein 18 kDa (TSPO) ligand etifoxine in an animal model of anxiety: Line- and sex-dependent effects on emotionality, stress reactivity, spine density, oxytocin receptors, steroids, and microbiome composition. Neuropharmacology, 2025, 266, pp.110282. ⟨10.1016/j.neuropharm.2024.110282⟩. ⟨inserm-05354144⟩
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- Sabina Luchetti, Matthew R J Mason, Philippe Liere, Antoine Pianos, Sara Cossu, et al.. Multiple sclerosis lesions exhibit sex-specific steroid changes. Neurobiology of Disease, 2025, 214, pp.107040. ⟨10.1016/j.nbd.2025.107040⟩. ⟨inserm-05354135⟩
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2023
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- Neïké Fernandez, Anthony Petit, Antoine Pianos, Léna Haddad, Michael Schumacher, et al.. Aging Is Associated With Lower Neuroactive Steroids and Worsened Outcomes Following Cerebral Ischemia in Male Mice. Endocrinology, 2023, 164 (1), pp.bqac183. ⟨10.1210/endocr/bqac183⟩. ⟨inserm-04509347⟩
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- ref_biblio
- Philippe Liere, Guo-Jun Liu, Antoine Pianos, Ryan J Middleton, Richard B Banati, et al.. The Comprehensive Steroidome in Complete TSPO/PBR Knockout Mice under Basal Conditions. International Journal of Molecular Sciences, 2023, 24 (3), pp.2474. ⟨10.3390/ijms24032474⟩. ⟨inserm-05354165⟩
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2021
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- Agustina Lara, Iván Esperante, Maria Meyer, Philippe Liere, Noelia Di Giorgio, et al.. Neuroprotective Effects of Testosterone in Male Wobbler Mouse, a Model of Amyotrophic Lateral Sclerosis. Molecular Neurobiology, 2021, 58 (5), pp.2088-2106. ⟨10.1007/s12035-020-02209-5⟩. ⟨inserm-04509472⟩
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2020
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- Jason J Paris, Philippe Liere, Sarah Kim, Fakhri Mahdi, Meagan E Buchanan, et al.. Pregnane steroidogenesis is altered by HIV-1 Tat and morphine: Physiological allopregnanolone is protective against neurotoxic and psychomotor effects. Neurobiology of Stress, 2020, 12, pp.100211. ⟨10.1016/j.ynstr.2020.100211⟩. ⟨inserm-05354193⟩
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2018
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- Olesya T Shevchouk, Samar Ghorbanpoor, Ed Smith, Philippe Liere, Michael Schumacher, et al.. Behavioral evidence for sex steroids hypersensitivity in castrated male canaries. Hormones and Behavior, 2018, 103, pp.80 - 96. ⟨10.1016/j.yhbeh.2018.06.004⟩. ⟨inserm-05354237⟩
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2015
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- Magalie Fréchou, Shaodong Zhang, Philippe Liere, Brigitte Delespierre, Nouha Soyed, et al.. Intranasal delivery of progesterone after transient ischemic stroke decreases mortality and provides neuroprotection. Neuropharmacology, 2015, 97, pp.394 - 403. ⟨10.1016/j.neuropharm.2015.06.002⟩. ⟨inserm-05354335⟩
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2010
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- Philippe Liere, Antoine Pianos, Bernard Eychenne, Annie Cambourg, Karl Bodin, et al.. Analysis of pregnenolone and dehydroepiandrosterone in rodent brain: cholesterol autoxidation is the key. Journal of Lipid Research, 2010, 50 (12), pp.2430 - 2444. ⟨10.1194/jlr.m900162-jlr200⟩. ⟨inserm-05357203⟩
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2004
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- Philippe Liere, Antoine Pianos, Bernard Eychenne, Annie Cambourg, Suya Liu, et al.. Novel lipoidal derivatives of pregnenolone and dehydroepiandrosterone and absence of their sulfated counterparts in rodent brain. Journal of Lipid Research, 2004, 45 (12), pp.2287 - 2302. ⟨10.1194/jlr.m400244-jlr200⟩. ⟨inserm-05357229⟩
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2000
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- Ṕhilippe Liere, Yvette Akwa, Sebastien Weill-Engerer, Bernard Eychenne, Paul Robel, et al.. Validation of an analytical procedure to measure trace amounts of neurosteroids in brain tissue by gas chromatography-mass spectrometry. Journal of Chromatography B Biomedical Sciences and Applications, 2000, 739 (2), pp.301-312. ⟨10.1016/s0378-4347(99)00563-0⟩. ⟨inserm-05357479⟩
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Poster communications
2020
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- Ghylène Goudet, Philippe Liere, Lydie Nadal-Desbarats, Antoine Pianos, Doryan Grivault, et al.. Steroidome and metabolome analysis in saliva from immature to pubertal gilts to identify potential biomarkers of receptivity to boar effect. 20. Organic World Congress 2020, Sep 2020, Rennes, France. ⟨hal-03903400⟩
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